Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneurons
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چکیده
منابع مشابه
Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneurons.
We examined the potential role of fibroblast growth factor 5 (FGF-5) as a target-derived trophic factor for spinal motoneurons. Northern analysis of total RNA from rat skeletal muscle revealed an FGF-5 mRNA transcript both during the period of embryonic motoneuron death and in the adult. Recombinant human FGF-5 supported the survival of highly enriched cultures of embryonic chick motoneurons. S...
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ژورنال
عنوان ژورنال: Neuron
سال: 1993
ISSN: 0896-6273
DOI: 10.1016/0896-6273(93)90327-n